The McMunn and Yates building supply store in Eriksdale was destroyed by fire early Thursday morning.
The fire department received the call around 4:30 a.m.
Residents are thanking the fire departments in Eriksdale, Lundar, Ashern and Mossehorn for their efforts.
All four crews were battling the blaze for nearly six hours.
The building is considered a total loss, and there are no injuries to report.
The blaze has also temporarily closed the Eriksdale COVID-19 Testing Site down the street.
The cause of the fire is unknown at this time, and the Fire Commissioners Office is investigating.